TRICHLOROACETIC ACID Chemical Compatibility

Trichloroacetic Acid (TCA, CCl3COOH, CAS 76-03-9) is a white, moisture-absorbing crystalline solid that melts near 135°F (57°C) and dissolves to form a strong, corrosive acid. It is used in laboratories to precipitate proteins and DNA, in medical chemical peels and wart removal, and as a reagent in organic synthesis. TCA solutions cause severe burns, so storage requires corrosion-resistant tanks and fittings. Use the compatibility ratings to choose the right tank resin, fittings and gaskets.

At a glance

Polypropylene is the most economical tank material for Trichloroacetic Acid, rated Excellent. Nylon and PVDF (Kynar®) are also rated Good or better. Avoid aluminum hardware. Rated Fair (contact us before use): HDPE tanks, HDPE fittings, Viton® gaskets and 316 stainless steel hardware.

  • Excellent No or minor effect. Recommended.
  • Good Slight effect. Generally suitable.
  • Fair Moderate effect. Limited or conditional use — contact us.
  • Not Recommended Severe effect. Do not use.
  • No Data Not tested. Contact us before use.

Tank Resins

How Trichloroacetic Acid works with the plastics used to make our storage tanks.

Material Rating
HDPE Fair
Polypropylene Excellent
Nylon Good
PVDF (Kynar®) Good

Fittings

How Trichloroacetic Acid works with the plastics used for tank fittings.

Material Rating
HDPE Fair
PVC Good
CPVC No Data
Polypropylene Excellent
PVDF Good

Gaskets & O-Rings

How Trichloroacetic Acid works with gasket and O-ring materials.

Material Rating
Buna-N No Data
EPDM Good
Viton® Fair

Metals

How Trichloroacetic Acid works with the metals used for fittings and bolts.

Material Rating
316 Stainless Steel Fair
Hastelloy Good
Titanium No Data
Aluminum Not Recommended

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